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目的 探讨膀胱癌和癌前病变膀胱乳头状瘤的性质及其生物学行为 ,为临床进一步治疗和预后判断提供病理学依据。方法 应用流式细胞术和细胞图象光度术测量和分析膀胱癌与膀胱乳头状瘤的细胞DNA含量和倍体增殖状态进行比较研究。结果 5 0例膀胱癌细胞的DNA含量和异多倍体出现率较膀胱乳头状癌的DNA含量和异多倍体出现率高出 1倍～ 3倍多。结论 测定膀胱肿瘤中的癌与乳头状瘤DNA含量及倍体测定可作为膀胱肿瘤生物学行为和预后判断的重要指标
Objective To investigate the nature and biological behavior of bladder cancer and precancerous lesions of the papillomatosis and to provide the pathological basis for clinical further treatment and prognosis. Methods Flow cytometry and cell image spectrophotometry were used to measure and analyze the DNA content and the multiplication state of bladder cancer and papilloma of bladder. Results The DNA content and the occurrence rate of heteropolyplasia in 50 cases of bladder cancer cells were more than three times as much as those of the papillary carcinoma of the bladder. Conclusion The determination of DNA content and ploidy in cancer and papilloma of bladder tumor can be used as an important indicator of the biological behavior and prognosis of bladder tumor