缺氧是导致胎儿及新生儿中枢神经系统损伤最常见的原因。多发生于围产期伴有酸中毒、贫血及高血压的一些胎盘病理和孕妇疾病时。据多数研究表明,导致婴儿中枢神经损伤的障碍多发生于产前期,40%发生于分娩期,5%发生于产后期。本文对109例围产期中枢神经损伤的病例进行了分析。产前期主要危险因素为孕妇年龄不利于分娩者占20%(<18岁或>40岁);生活、社会环境不良40例,从事繁重体力劳动或受生产有害物(噪音、振动、化学物质)影响者20例;慢性病26例,其中 Hypoxia is the most common cause of central nervous system injury in the fetus and newborn. Occur in perinatal with acidosis, anemia and hypertension in some placental pathology and maternal diseases. Most studies show that the most common cause of central nervous injury in infants occurs in the prenatal period, 40% in the delivery period, and 5% in the postpartum period. In this paper, 109 cases of perinatal central nervous system injury were analyzed. The main risk factors for prenatal period are: 20% (<18 years or> 40 years) of pregnant women are not conducive to childbirth; 40 cases of poor living and social environment, heavy manual labor or production of harmful substances (noise, vibration, chemicals) 20 cases of impact; chronic disease in 26 cases, of which