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目的探讨采用甲氨蝶呤联合米非司酮对异位妊娠进行保守治疗的临床效果。方法随机选取郏县妇幼保健院2012年7月—2014年3月期间收治的异位妊娠患者90例,按照用药方法的不同将其分为实验组和对照组,其中对照组患者单用甲氨蝶呤进行治疗,实验组采用甲氨蝶呤联合米非司酮进行治疗,对比两组患者的临床治疗效果及其不良反应的发生情况。结果实验组患者的临床治愈率、住院时间及血β-HCG恢复时间均明显优于对照组(P<0.05);两组患者不良反应的发生情况差异无显著性(P>0.05)。结论采用甲氨蝶呤联合米非司酮对异位妊娠进行保守治疗,效果显著,安全可靠,建议在临床上进一步推广。
Objective To investigate the clinical effect of methotrexate combined with mifepristone on conservative treatment of ectopic pregnancy. Methods 90 cases of ectopic pregnancy admitted to Pixian MCH from July 2012 to March 2014 were randomly divided into experimental group and control group according to the method of medication, The treatment group was treated with methotrexate and mifepristone, and the clinical effects and adverse reactions of the two groups were compared. Results The clinical cure rate, hospital stay and blood β-HCG recovery time in the experimental group were significantly better than those in the control group (P <0.05). There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion Methotrexate combined with mifepristone conservative treatment of ectopic pregnancy, the effect is significant, safe and reliable, it is recommended to further promote the clinical.