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肿瘤的形成受遗传学修饰和表观遗传修饰的影响,DNA甲基化是真核细胞正常的修饰方式,是一种重要的表观遗传修饰,其异常在肿瘤等多种疾病的发生、发展中有重要的作用。DNA甲基化是遗传外修饰的重要的调控方式,也是脊椎动物DNA唯一的自然修饰方式。DNA甲基化后核苷酸顺序未变,而基
The formation of tumors is influenced by genetic modification and epigenetic modification. DNA methylation is a normal modification of eukaryotic cells and is an important epigenetic modification. Its abnormalities are involved in the occurrence and development of many diseases such as tumors There is an important role. DNA methylation is an important control of genetic modification, but also the only natural modification of vertebrate DNA. Nucleotide sequence after DNA methylation has not changed, while the base