男性不育症病因包括少精子症、弱精子症、畸形精子症、无精子症及抗精子抗体所致的免疫性不育等,其中少、弱、畸形精子症患者较为多见,其染色体异常是引起不育、流产、死胎、先天缺陷、脑发育迟缓的一个重要原因[1]。因为绝大多数染色体异常是在减数分裂过程中产生的,因此,直接 The causes of male infertility include oligospermia, asthenospermia, schizophrenia, azoospermia and immune sterility caused by anti-sperm antibodies, of which, less, malformed sperm patients are more common, the chromosomal abnormalities Is caused by infertility, miscarriage, stillbirth, birth defects, brain growth retardation is an important reason [1]. Because the vast majority of chromosomal abnormalities are produced during meiosis, therefore, directly