论文部分内容阅读
为了探讨不同喘病免疫学变化规律及喘息发生机理,我们对320例喘病进行了T淋巴细胞亚群、Ig和补体等15项免疫学指标检测。结果:与健康儿比较,喘病的IgG、IeA、IgD、IgE均显著升高,其中IgD和IeE哮喘高于喘支,喘支高于毛支。T淋巴细胞亚群中的CD_3、CD_4、CD_8和NKCA均显著低于健康儿,CD_4/CD_8,比值显著升高。RBC—IC花环率均显著高于健康儿,C_4仅哮喘儿童升高,表明喘病患儿存在着多方面免疫功能失调,其中以CD_8降低和CD_4相对亢进最重要。同时,三者存在相似而又程度各不相同的免疫学变化,进一步证明三者间关系非常密切而复杂。
In order to investigate the different rules of asthmatic immunology and mechanism of wheezing, we detected 15 immunological indexes such as T lymphocyte subsets, Ig and complement in 320 asthmatic patients. Results: Compared with healthy children, the IgG, IeA, IgD and IgE of wheezing were significantly higher than those of healthy children. The IgD and IeE asthma were higher than those of asthma and the asthma was higher than the branch of bronchi. The ratios of CD_3, CD_4, CD_8 and NKCA in T lymphocyte subsets were significantly lower than those in healthy children, with a significant increase in the ratio of CD_4 / CD_8. RBC-IC rosette rate were significantly higher than healthy children, C_4 only asthma children increased, indicating that children with asthma in many aspects of immune dysfunction, including CD_8 and CD_4 relative hyperthyroidism is the most important. At the same time, there are similar and varying degrees of immunological changes among the three, which further proves that the relationship between the three is very close and complicated.