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微循环障碍是感染性休克的中心环节,复苏的目标是恢复组织灌注和细胞氧代谢平衡。传统的临床指标血压、心率、尿量、皮温等难以评价组织灌注和细胞氧代谢复苏效果,最佳复苏评估指标需要包括血流动力学、组织灌注及细胞氧代谢相关指标。早期目标化治疗所包含的综合性指标平均动脉压(MAP)≥65mmHg(1mmHg=0.133kPa),中心静脉压(CVP)8～12mmHg,尿量>0.5mL(/kg·h),中心静脉血氧饱和度(ScvO2)>65%或混合静脉血氧饱和度(SvO2)>70%,可以作为临床常规评估的重要依据。
Microcirculation is the central part of septic shock, the goal of recovery is to restore tissue perfusion and cell oxygen metabolism balance. Traditional clinical indicators such as blood pressure, heart rate, urine output, skin temperature and so difficult to evaluate the effect of tissue perfusion and oxygen metabolism and recovery, the best indicators of assessment of recovery need to include hemodynamics, tissue perfusion and cell oxygen metabolism related indicators. Early target of comprehensive treatment of the indicators include the average arterial pressure (MAP) ≥ 65mmHg (1mmHg = 0.133kPa), central venous pressure (CVP) 8 ~ 12mmHg, urine output> 0.5mL (/ kg · h), central venous blood ScvO2> 65% or mixed venous oxygen saturation (SvO2)> 70%, can be used as an important basis for routine clinical evaluation.