作者在本文报道13例由优降糖引起的长时间低血糖症,均为1983—1984年间因低血糖首次就诊、符合糖尿病诊断标准并有服用优降糖的病史、血糖低于50mg/dl、用葡萄糖治疗后血糖仍低于50mg/dl超过12小时的患者。本组病例平均年龄76.2(68—89)岁;入院时平均最低血糖为29.8±2.9(10—6)mg /dl。其中7例低血糖发生在用优降糖治疗4开始后1周内,2例在仅服用一次优降糖5mg后即发生低血糖。尽管用20—50％葡萄糖静脉注射和5 10％葡萄糖持续静滴,但仍有8例低血糖状态持 The authors report 13 cases of hypoglycemia caused by glyburide for a long time, are 1983-1984 first visit due to hypoglycemia, meet the diagnostic criteria for diabetes and taking glyburide history, blood glucose less than 50mg / dl, Patients with glucose below 50 mg / dl for more than 12 hours after treatment with glucose. The average age of patients in this group was 76.2 (68-89) years; mean lowest blood glucose at admission was 29.8 ± 2.9 (10-6) mg / dl. Seven of the hypoglycemic events occurred within one week after the initiation of glyburide treatment 4, and two had hypoglycemia after taking only 5 mg of glyburide once. Although intravenous injection of 20-50% glucose and continuous intravenous infusion of 5-10% glucose, 8 cases remained hypoglycemic