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关于植物对调节生物体血压的重要物质血管紧张素转换酶(ACE)抑制作用的研究已有报道。作者对呈现降压作用的天然药物的新鲜植物和生药,分别用甲醇、氯仿、石油醚、90%甲醇和水的提取物,以马尿酸(HIP)分光光度法和二肽(PEP)荧光法作为ACE抑别活性的测定。结果有38种生药的各提取物呈现35%以上的抑制活性:在HIP 法中有豨莶草、黄芪、鸡血藤的90%甲醇提取物,酸枣仁的石油醚提取物;PEP 法中黄芪的甲醇、水、氯仿、90%甲醇提取物,瞿麦氯仿提取物和山
Research on the inhibition of angiotensin-converting enzyme (ACE), an important substance that modulates the blood pressure of living organisms, has been reported. The authors studied the fresh plants and crude drugs of natural medicine that exerted antihypertensive effects, respectively using the extracts of methanol, chloroform, petroleum ether, 90% methanol and water, HIP spectrophotometry and dipeptide (PEP) As a measure of ACE inhibitory activity. RESULTS: The extract of 38 kinds of crude drugs showed more than 35% inhibitory activity: 90% methanol extract of Achnatherum splendens, Astragalus and Millettia sedum and petroleum ether extract of Spinach root in HIP method; Astragalus membranaceus Methanol, Water, Chloroform, 90% Methanol Extract, Quercetin Chloride Extract and Mountain