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目前体外受精-胚胎移植(IVF-ET)每一治疗周期的临床妊娠率仍只有近20％。已经对可能作为IVF-ET结果预测指标的几个卵巢功能参数进行了研究。11-β羟类固醇脱氢酶(11β-HSD)是其中之一。11β-HSD的作用是将皮质醇转变为皮质酮而加以灭活。为确定卵巢11β-HSD活性与IVF-ET结果的关系及其在患者的连续治疗周期中有否变化,作者对137名妇女172个IVF-ET治疗周期(137个初次周期,35个重复周期)的有关数据进行了回顾性相关分析。11β-HSD活性测定及
At present, the IVF-ET pregnancy pregnancy rate is still only about 20%. Several ovarian function parameters that may serve as predictors of IVF-ET outcome have been studied. 11-beta hydroxysteroid dehydrogenase (11 beta-HSD) is one of them. The role of 11 [beta] -HSD is to convert cortisol to corticosterone and inactivate it. To determine the relationship between ovarian 11β-HSD activity and IVF-ET outcome and whether there was any change in the patient’s continuous treatment cycle, we evaluated 172 IVF-ET treatment cycles (137 initial cycles, 35 repetitive cycles) in 137 women, The data were analyzed retrospectively. 11β-HSD activity and determination