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目的探讨大黄汤导泻治疗急性有机磷农药中毒的临床疗效。方法选取2013年5月—2015年5月任丘市人民医院收治的急性有机磷农药中毒患者60例,按照入院顺序分为试验组与对照组,各30例。两组患者入院后均予以常规综合治疗,对照组患者予以20%甘露醇导泻,试验组患者予以大黄汤导泻。结果试验组患者总有效率高于对照组,差异有统计学意义(P<0.05);试验组患者首次排便时间、全血胆碱酯酶水平复常时间短于对照组,日排便次数多于对照组,差异有统计学意义(P<0.05);两组患者均未出现严重不良反应。结论大黄汤导泻治疗急性有机磷农药中毒的临床疗效显著,可缩短患者首次排便时间及全血胆碱酯酶水平复常时间,增加日排便次数,且不良反应少。
Objective To investigate the clinical efficacy of rhubarb decoction in the treatment of acute organophosphorus pesticide poisoning. Methods Sixty patients with acute organophosphorus pesticide poisoning admitted to Renqiu People’s Hospital from May 2013 to May 2015 were selected and divided into experimental group and control group according to admission sequence, with 30 cases in each group. Two groups of patients were treated with conventional comprehensive treatment, the control group of patients with 20% mannitol catharsis, the experimental group of patients with rhubarb soup catharsis. Results The total effective rate of the experimental group was higher than that of the control group (P <0.05). The first defecation time, the duration of normalization of the whole blood cholinesterase level in the experimental group were shorter than those in the control group, Control group, the difference was statistically significant (P <0.05); two groups of patients did not appear serious adverse reactions. Conclusion rhubarb decoction in the treatment of acute organophosphorus pesticide poisoning clinical significant effect, can shorten the time of patients with first defecation and the whole blood cholinesterase level of normal time, increase the number of days of defecation, and less adverse reactions.