鼻病毒是普通感冒的主要病因 ,但一直以来人们认为鼻病毒仅与上呼吸道感染有关 ,近来发现无论在儿童还是在成人中 ,鼻病毒也是急性哮喘恶化的诱因 ,但这种恶化是由于下呼吸道被直接感染还是由于上呼吸道感染而间接导致的呢 ?作者通过体外鼻病毒感染原代培养的人支气管上皮细胞 Rhinovirus is the main cause of common cold, but rhinovirus has long been thought to be associated with upper respiratory tract infection. Recently it has been found that rhinovirus is also a cause of acute asthma exacerbation both in children and adults, but this deterioration is due to lower respiratory tract Be directly or indirectly caused by upper respiratory tract infection? The author in vitro rhinovirus infection of primary cultured human bronchial epithelial cells