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目的采用交感神经皮肤反应(SSR)检测方法,探讨临床中常用的血液净化方式的临床效果。方法随机选取梅州市人民医院长期透析伴尿毒症植物神经病变患者230例,将其分为血液普通透析(HD)组102例、血液滤过透析(HDF)组60例、血液灌流加透析(HD+HP)组44例、腹膜透析(PD)组24例,均采用SSR检测。结果研究对象经对症治疗后,SSR改善率依次为PD组100.00%、HDF组100.00%、HD+HP组66.68%、HD组11.75%,组间对比差异有统计学意义(P<0.05)。结论 HD+HP、PD及HDF治疗尿毒症患者有良好的临床疗效,而采用HD治疗无明显临床效果。
Objective To investigate the clinical effect of blood purification methods commonly used in clinical practice by using the method of sympathetic skin reaction (SSR). Methods Totally 230 patients with long-term hemodialysis and uremia autonomic neuropathy in Meizhou People’s Hospital were randomly divided into two groups: 102 cases in HD group, 60 cases in HDF group, HD in hemodialysis plus HD + HP) group and 44 cases of peritoneal dialysis (PD) group, all using SSR test. Results After the symptomatic treatment, the improvement rate of SSR was 100.00% in PD group, 100.00% in HDF group, 66.68% in HD + HP group and 11.75% in HD group, the difference was statistically significant (P <0.05). Conclusion HD + HP, PD and HDF treatment of uremic patients have good clinical efficacy, and no obvious clinical effect using HD treatment.