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目的研究2型糖尿病微量白蛋白尿与颈总动脉内膜中层厚度(CIMT)的关系。方法选取2型糖尿病150例,根据尿微量白蛋白排泄率(UAER)分为DM-A组52例(UAER<20μg/min),DM-B组54例(UAER在20~200μg/min之间),DM-C组54例(UAER>200μg/min);并设立正常对照组20例,测定其颈总动脉内膜中层厚度,观察尿微量白蛋白与颈总动脉内膜中层厚度的关系。结果糖尿病组CIMT明显高于正常对照组,糖尿病各亚组中,DM-B组及DM-C组的CIMT均显著高于DM-A组(P<0.01),DM-C组的CIMT显著高于DM-B组(P<0.01)。结论尿微量白蛋白排泄率越高,颈总动脉内中膜中层厚度增加。
Objective To study the relationship between microalbuminuria and carotid artery intima-media thickness (CIMT) in type 2 diabetes. Methods 150 cases of type 2 diabetes mellitus were divided into two groups according to urinary albumin excretion rate (UAER): 52 cases (UAER <20μg / min), 54 cases DMA (UAER between 20 ~ 200μg / min) ) And DM-C group (UAER> 200μg / min). The normal control group (n = 20) was established. The intima-media thickness of common carotid artery was measured and the relationship between urinary microalbumin and intima-media thickness of common carotid artery was observed. Results The CIMT in diabetes mellitus group was significantly higher than that in normal control group (P <0.01). The CIMT in DM-C group and DM-C group was significantly higher than that in DM-C group In DM-B group (P <0.01). Conclusion Urine microalbumin excretion rate is higher, and the carotid artery intima-media thickness increases.