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冠状动脉慢血流现象是一种由于内皮功能不全引起的微血管功能障碍性疾病。目前认为男性、吸烟、肥胖、高血尿酸水平、糖耐量异常、高血浆同型半胱氨酸水平、血小板功能和形态异常是其致病的高危因素。冠状动脉慢血流现象可能是系统性疾病的一种临床表现，其发病机制尚不清楚，研究提示微血管功能失调及障碍、内皮细胞受损和功能障碍、内皮活化及炎症、基因变异与冠状动脉慢血流现象的发病密切相关。“,”Coronary slow flow phenomenon ( CSFP) is a kind of microvascular function disorder caused by endothelial dysfunction. High risk factors for CSFP include smoking, obesity, high blood uric acid level and abnormal glucose tolerance, high plasma homocysteine levels, and abnormal platelet function and form.CSFP may be a single clinical presentation of a systemic disease, however, the pathogenesis of CSFP has not yet been completely understood.Several mechanisms have been proposed for CSFP such as microvascular dysfunction, im-paired endothelial cells, endothelial activation and dysfunction, inflammation, and genetic variation.