患者女性,40岁,已婚,干部。因反复咳嗽10余年,症状加重伴活动后胸闷、气促2年于1990年8月15日就诊。患者10年前开始咳嗽,为间断性轻咳,夜间多发,无痰及喘息。以后每年以冬春季节好发,仍以夜间为著,有时咳醒,少量白痰,无发热。近2年来四季均有咳嗽,昼夜发作,伴活动后胸闷气促。曾在省、市级医院多次就诊,均按“慢性支气管炎”治疗,常服抗生素及止咳药物,病情迁延未愈。发作期多次体检两肺未闻哮鸣音。既往 Patient female, 40 years old, married, cadre. Due to repeated cough for more than 10 years, with aggravating symptoms chest tightness, shortness of breath 2 years in August 15, 1990 treatment. The patient began to cough 10 years ago, intermittent light cough, multiple attacks at night, no sputum and wheezing. Spring and winter each year after a good hair, still at night, sometimes cough, a small amount of white sputum, no fever. The past two years, all seasons have cough, day and night episodes, chest tightness with activity shortness of breath. Once in the provincial and municipal hospitals for multiple visits, according to “chronic bronchitis” treatment, often taking antibiotics and cough medicine, the disease continued to heal. Multiple episodes of physical examination did not hear wheezing two lungs. Past