论文部分内容阅读
白细胞介素-18(IL-18)是一种重要的细胞免疫调节因子,幽门螺杆菌(H.pylori)能促进胃上皮细胞和黏膜固有层单核细胞分泌IL-18,参与包括慢性胃炎、消化性溃疡、胃癌和胃黏膜相关淋巴组织(MALT)淋巴瘤等多种胃十二指肠疾病的发生。本文就IL-18与H.pylori感染的关系及其致病作用研究进展作一综述。
Interleukin-18 (IL-18) is an important cellular immune regulator. Helicobacter pylori (H.pylori) can promote the secretion of IL-18 by monocytes in gastric epithelial cells and lamina propria, involving chronic gastritis, Peptic ulcer, gastric cancer and gastric mucosa associated lymphoid tissue (MALT) lymphoma and other gastroduodenal diseases. This article reviews the relationship between IL-18 and H. pylori infection and the progress of its pathogenesis.