目的:制备辛夷鼻用粉雾剂的固体粉末。方法:筛选辛夷挥发油提取方法,优选其提取工艺;采用包合工艺使液体药物粉末化,筛选最佳包合方法,优选包合工艺。结果:最佳提取工艺为水蒸气蒸馏法1,2倍水、浸泡4h、提取5h;最佳包合工艺为研磨法,V油∶mβ-CD=1∶103,倍水,研磨60min。结论:提取、包合工艺合理可靠,包合产物可作为鼻用粉雾剂的原料。 Objective: To prepare the solid powder of Magnolia nasal powder. Methods: The extraction method of volatile oil from Magnolia biondii was selected, and its extraction process was optimized. The liquid drug was powdered by inclusion process and the best inclusion method was screened, preferably inclusion process. Results: The best extraction process was steam distillation 1, 2 times water, soak 4h, extraction 5h; the best inclusion process for the grinding method, V oil: mβ-CD = 1:103 times the water, grinding 60min. Conclusion: The extraction and inclusion process is reasonable and reliable, and the inclusion product can be used as the raw material of nasal powder.