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目的探讨伽玛刀治疗原发性与继发性癫痫疗效。方法回顾性分析我院2002年至2010年接受伽玛刀治疗并且资料完整的155例癫痫病人发作情况,原发性癫痫伽玛刀治疗边缘剂量15~25Gy,继发性癫痫8~20Gy。结果随访时间13~135个月,平均67个月,76例原发性癫痫,有效率68.4%,79例继发性癫痫,有效率79.7%,两者之间无统计学差异,但继发性癫痫满意及显著改善比率较高。结论伽玛刀治疗癫痫安全、有效、且并发症少,继发性癫痫伽玛刀治疗效果可能更好。
Objective To investigate the therapeutic effect of gamma knife on primary and secondary epilepsy. Methods A retrospective analysis of 155 cases of epilepsy in our hospital from 2002 to 2010 with gamma knife treatment and complete data was performed. The primary epilepsy gamma knife was used to treat 15 ~ 25 Gy marginal dose and 8-20 Gy of secondary epilepsy. Results The follow-up time ranged from 13 to 135 months with an average of 67 months. There were 76 cases of primary epilepsy with an effective rate of 68.4% and 79 cases of secondary epilepsy with an effective rate of 79.7%. There was no significant difference between the two groups Satisfactory and significantly improved rate of sexual epilepsy. Conclusion gamma knife treatment of epilepsy is safe and effective, and the complications less, the treatment of secondary epilepsy gamma knife may be better.