目的探讨经单鼻孔蝶窦入路切除垂体瘤的显微手术技巧及术后处理。方法对12例经CT扫描和MRI检查确诊为垂体瘤患者,采用经鼻蝶入路切除肿瘤。术中将扩鼻器直抵蝶窦前壁,将鼻中隔完整地推向对侧,凿除蝶窦前壁骨质,经鞍底切除肿瘤。结果行肿瘤10例全切除,2例大部分切除,无严重并发症发生,无死亡。结论经单鼻孔蝶窦入路切除垂体瘤创伤小,安全性高,并发症少,术后病人恢复快,省时易行,对于位于鞍内和大部位于鞍内的垂体瘤是一种有效的术式。 Objective To investigate the microsurgical technique and postoperative treatment of pituitary tumors treated with a single nostril sphenoid sinus approach. Methods Twelve patients diagnosed as pituitary tumors by CT scan and MRI were treated with a transnasal approach. In the operation, the nasal expander is directly abutted against the anterior wall of the sphenoid sinus, and the nasal septum is completely pushed to the contralateral side. The bone in the anterior wall of the sphenoid sinus is chiseled and the tumor is removed through the saddle base. Results 10 patients underwent total resection of the tumor, and most of the resections were performed in 2 patients. No serious complications occurred and no death occurred. Conclusions The transnasal sphenoid sinus approach has minimal trauma, high safety, and few complications. The patient recovers quickly after surgery and is time-saving. It is effective for pituitary tumors located in the saddle and in the saddle. Technique.