免疫系统对急性中耳感染的重要意义已为人们所熟知,但它在慢性感染中的作用则尚未被充分注意。本文列举了3例慢性中耳炎患者,以前都做过多次乳突根治凿开术,均因防御机制的削弱,术后反复感染而增加了伤口愈合的困难,后经详查始发现均有免疫缺陷。经局部使用IgA,或手术前,后注射γ-球蛋白或输新鲜血浆治疗后皆获得惊人的效果。这3例病人给人们提供了免疫与慢性耳感染 The importance of the immune system for acute middle ear infections is well known, but its role in chronic infection has not been adequately addressed. This article lists 3 patients with chronic otitis media, have done a number of radical mastectomy, are due to the weakening of the defense mechanism, repeated infection after surgery and increased the difficulty of wound healing, after investigation found that all have been immune defect. After local use of IgA, or before and after injection of γ-globulin or lose fresh plasma treatment are surprising results. These three patients provided people with immune and chronic ear infections