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子宫内膜异位症(endometriosis,Ems)是一种具有“恶性行为”的良性疾病,它的发病机制至今尚未完全明确,最被公认的Sampson经血逆流种植学说指出新血管生成是Ems发生的必要条件,大量的基础实验和临床研究也证实了该观点。本文仅就血管促进因子在新血管生成中的作用以及血管生成抑制剂对Ems的治疗作用两方面做一综述。
Endometriosis (Ems) is a benign disease with “malignant behavior”. The pathogenesis of endometriosis is not yet fully understood. The most accepted Sampson theory of menopause implies that neoangiogenesis is necessary for Ems Conditions, a large number of basic experiments and clinical studies also confirmed this view. This article reviews only the role of angiogenic factors in neovascularization and the therapeutic effects of angiogenesis inhibitors on Ems.