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目的 探讨CEA对大肠癌肝转移早期诊断的临床意义 .方法 采用免疫放射法测定 46例大肠癌患者血清中CEA .结果 CEA在Duke’sA ,B期大肠癌患者的阳性率与在Duke’sC ,D期大肠癌患者的阳性率比较 ,差异显著 (P <0 .0 5 ) ;CEA在大肠癌肝转移组中的阳性率与在大肠癌其他组织或脏器转移组中的阳性率比较 ,差异显著 .结论 CEA与大肠癌的临床分期密切相关 ,CEA值的异常升高 ,可视为大肠癌肝转移的高危信号
Objective To investigate the clinical significance of CEA in the early diagnosis of liver metastasis of colorectal cancer.Methods Immunoradiometric assay was used to measure the serum CEA in 46 patients with colorectal cancer.ResultsThe positive rate of CEA in Duke’sA,B stage colorectal cancer patients was in Duke’sC, There was significant difference in the positive rate of patients with stage D colorectal cancer (P < 0.05). The positive rate of CEA in colorectal liver metastasis was compared with the positive rate of colorectal cancer in other tissues or organ metastases. Significant. Conclusion CEA is closely related to the clinical stage of colorectal cancer. Abnormal increase of CEA value can be regarded as a high risk signal for liver metastasis of colorectal cancer.