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目的观察降钙素原在诊断新生儿肺炎中的变化特点。方法选取84例新生儿肺炎患儿和50例健康新生儿作为研究对象,检测2组新生儿血清降钙素原(PCT)、C-反应蛋白(CRP)和外周血白细胞计数(WBC),比较2组新生儿血清PCT、CRP和WBC水平差异及各项指标的阳性率。结果新生儿肺炎组PCT、CRP和WBC水平明显高于健康新生儿组,差异均有统计学意义(P<0.05)。新生儿肺炎组PCT阳性率(91.67%)明显高于CRP(64.29%)和WBC(51.90%),差异均有统计学意义(P<0.05)。结论新生儿肺炎患儿血清PCT水平明显升高,检测PCT有助于诊断新生儿肺炎提供依据。
Objective To observe the changes of procalcitonin in the diagnosis of neonatal pneumonia. Methods Eighty-four neonates with pneumonia and 50 healthy newborns were enrolled in this study. Serum procalcitonin (PCT), C-reactive protein (CRP) and peripheral blood leukocyte count (WBC) were measured in two groups. The difference of serum PCT, CRP and WBC levels and the positive rate of each index between two groups of newborns. Results The levels of PCT, CRP and WBC in neonates with pneumonia were significantly higher than those in healthy neonates (P <0.05). The positive rate of PCT in neonatal pneumonia group (91.67%) was significantly higher than that in CRP (64.29%) and WBC (51.90%), the difference was statistically significant (P <0.05). Conclusion Serum PCT levels are significantly elevated in children with neonatal pneumonia, and the detection of PCT may be helpful to diagnose neonatal pneumonia.