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目的：探讨肾移植术后红细胞增多症与环孢素Ａ的关系。方法：对３０２例肾移植患者中７２例红细胞增多症者的血红蛋白水平变化，与环孢素Ａ服用剂量的关系，以及血环孢素Ａ水平等进行研究。结果：７２例患者平均血红蛋白峰值２００５４±１６９８ｇ／Ｌ，范围１６７ｇ／Ｌ～２３８ｇ／Ｌ；血球压积峰值５９±３％，范围５１％～６４％；血红蛋白增高初期血环孢素Ａ浓度明显高于对照组（Ｐ＜０００２～０００１）；３例停用环孢素Ａ血红蛋白降至正常；１３例血红蛋白值下降与环孢素Ａ服用剂量减少正相关（Ｐ＜００５～０００１）。结论：肾移植术后存在环孢素Ａ相关性红细胞增多症。
Objective: To investigate the relationship between Cytosporine A and polycythemia after renal transplantation. Methods: The changes of hemoglobin level in 72 cases of polycythemia patients with 302 renal transplant recipients were studied with the dose of cyclosporin A and the level of cyclosporin A. Results: The mean hemoglobin of 72 patients was 20054 ± 1698 g / L, ranging from 167 g / L to 238 g / L. The peak value of hematocrit was 59 ± 3%, ranging from 51% to 64%. Hemoglobin A concentration was significantly higher than that of the control group (P <0002 ~ 0001); 3 cases stopped cyclosporine A hemoglobin returned to normal; 13 cases of hemoglobin decreased with cyclosporine dose decreased (P < 0 05 ~ 0 001). CONCLUSIONS: Cyclosporin A-related polycythemia is present after kidney transplantation.