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目的 :探讨胰周神经离断术在晚期胰腺癌病人的应用价值。方法 :收集自 1 992年 1 0月～ 1 998年 8月间共 42例不能切除的胰腺癌病例 ,行剖腹探查或内引流术 2 4例 ,剖腹探查或内引流术加胰周神经离断术1 8例 ,分别观察这些病例术后腹痛变化、饮食情况和术后存活时间。结果 :前者无一例外地在术后短期内出现腹痛 ,且愈益加重 ,后期均需要强效镇痛药止痛 ,也因疼痛影响了进食 ,术后存活 2～ 1 1月 ,平均 ( 5.0 0±2 .32 )月 ;后者 7例病人出现腹痛 ,4例病人需要强效镇痛药止痛 ,术后短期内进饮食状况明显改善 ,术后存活 3～ 1 8月 ,平均 ( 7.0 0± 4.0 6)月。结论 :胰周神经离断术作为晚期胰腺癌的一种辅助治疗措施 ,方法简便 ,效果确实 ,不但能够有效地缓解疼痛 ,而且可以改善症状 ,延长存活时间
Objective: To investigate the value of peripancreatic neurotomy in patients with advanced pancreatic cancer. METHODS: A total of 42 cases of unresectable pancreatic cancer were collected from January 1990 to August 1998. Twenty-four patients underwent laparotomy or internal drainage, and laparotomy or internal drainage plus peripancreatic neurotomy was performed. Eighteen patients underwent surgery to observe the postoperative abdominal pain, diet, and postoperative survival. RESULTS: The former did not suffer from abdominal pain in the short term after operation, and they became worse. In the later period, they all required strong analgesics to relieve pain. They also affected the eating due to pain. The survival rate was 2 to 11 months, with an average of 5.0 ± 2.32 months; the latter 7 patients had abdominal pain, 4 patients required strong analgesics to relieve pain, the postoperative short-term diet improved significantly, postoperative survival 3 to 18 months, the average (7.0 0 ± 4.0 June. Conclusion : Peri-pancreatic nerve dissection is an adjunctive treatment for advanced pancreatic cancer. The method is simple and effective. It not only relieves pain effectively, but also improves symptoms and prolongs survival time.