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Noyes评定标准已广泛地用作标准方法对子宫内膜发育日期进行测定已30多年。除Noyes和Klaman外,尚无研究者报道这种测定法的准确性。作者设计了分析使用Noyes标准时标定组织学日期的结果:(1)观察者本人观看的变异;(2)受试者中周期之间的变异及其临床意义。受试者均为要求体外受精的不孕妇女,且都符合下列条件:月经周期规律,25～35天,且内分泌学有排卵的证据;在黄体期进行宫内膜活检(EB),且有充足的宫内膜进行组织学分析;在研究周期中
Noyes assessment standards have been widely used as standard methods for the determination of endometrial development for more than 30 years. With the exception of Noyes and Klaman, no investigators have reported the accuracy of this assay. The authors devised the results of analyzing histological dates when using the Noyes standard: (1) variability observed by the observer; and (2) variability between cycles in the subject and their clinical significance. Subjects were all infertile women who requested in vitro fertilization and all met the following criteria: regular menstrual cycle, 25-35 days, and evidence of ovulation in endocrinology; endometrial biopsy (EB) in the luteal phase with Histological analysis of adequate endometrium; during the study period