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患者,男,29岁.因上消化道出血入院.患者既往对磺胺、青霉素有过敏史.入院后给予5%葡萄糖氯化钠500mL、西咪替丁0.8g、氨甲环酸0.6g静脉补液止血治疗.5天后改为奥美拉唑(德国产)20mg口服,每日1次.服药50min后.患者全身瘙痒,颜面及双上肢斑丘疹,伴有心慌、寒战、头昏眼花、出冷汗,血压为11/8kPa,考虑为过敏反应.停止用药,立即给予苯海拉明20mg肌注,15min后未见好转.
Patient, male, age 29. Admitted to upper gastrointestinal tract due to upper gastrointestinal bleeding.Patients were previously allergic to sulfonamides and penicillin.After admission, they were given 500 mL of 5% dextrose and sodium chloride, 0.8 mg of cimetidine and 0.6 g of tranexamic acid Hemostatic treatment .5 days after the change to omeprazole (German) 20mg orally, day 1. After taking the drug 50min. Patients with systemic itching, facial and double upper extremity rash, accompanied by palpitation, chills, dizziness, cold sweat , Blood pressure 11 / 8kPa, considered as an allergic reaction to stop the medication, immediately given diphenhydramine 20mg intramuscular injection, no improvement after 15min.