通过用丹那唑治疗子宫内膜鼻位症患者，观察服用该药前后及停药后脂代谢水平指标及部分内分泌指标变化。结果：血清ＨＤＬ—ｃ、ＨＤＬ２－ｃ、ＨＤＬ３－ｃ及ＡｐｏＡ—Ｉ等水平显著下降，ＬＤＬ－ｃ及ＡｐｏＢ水平显著上升，ＬＤＬ／ＨＤＬ及ＡｐｏＢ／ＡｐｏＡ－Ⅰ两比值明显增大；Ｅ２水平显著下降，ＦＳＨ、ＬＨ及Ｔ水平没有明显变化；停药后２个月各指标均回到用药前水平，说明就脂代谢变化而言，丹那哇不适作长期连续治疗。亦对该药的使用进行了讨论，并从脂代谢角度对内膜异位症在治疗药物如何选择上提出了建议。 By treating patients with endometriosis with danazol, we observed the changes of lipid metabolism and some endocrine indexes before and after taking this medicine. Results: Serum levels of HDL-c, HDL2-c, HDL3-c and ApoA-I decreased significantly, the levels of LDL-c and ApoB increased significantly, and the ratios of LDL / HDL and ApoB / ApoA- Decline, FSH, LH and T levels did not change significantly; 2 months after stopping the indicators were returned to pre-drug levels, indicating that changes in lipid metabolism, Danna wow not suitable for long-term continuous treatment. The use of this drug was also discussed, and recommendations on how to choose the treatment of endometriosis from the perspective of lipid metabolism were suggested.