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1989年12月至1990年12月,我们用纳络酮治疗急性酒精中毒25例,疗效较为满意,现报道如下。临床资料 25例急性酒精中毒病人,男18例,女7例,年龄19～38岁,平均27岁,入院时烦躁、哭闹无常、站立不稳(共济失调期)7例,昏睡至深昏迷期18例;对照组病人25例,男22例,女3例,平均年龄29岁,两组病人饮酒数均在300～500ml。治疗方法对照组给予补液、维生素、胰岛素、烟酸等一般治疗,以加速乙醇氧化、排出,并辅以对症治疗,纳络酮组在上述治疗基础上给予50%葡萄糖20ml+纳络酮0.8mg,昏迷期患者于20分钟后重复给予1次,最大量可用至1.6～
December 1989 to December 1990, we use naloxone treatment of acute alcoholism in 25 cases, the effect is more satisfactory, are reported below. Clinical data 25 cases of acute alcoholism patients, 18 males and 7 females, aged 19 to 38 years old, an average of 27 years old, admitted to irritability, crap, unstable standing (ataxia) in 7 cases, lethargy to deep 18 cases of coma; control group of 25 patients, 22 males and 3 females, mean age 29 years old, two groups of patients drinking were 300 ~ 500ml. The treatment group was given fluid replacement, vitamins, insulin, niacin and other general treatment to accelerate ethanol oxidation and excretion, supplemented by symptomatic treatment, naloxone group on the basis of the above treatment given 50% glucose 20ml + naloxone 0.8mg, Coma patients were given once after 20 minutes, the maximum available to 1.6 ~