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为探讨衰老与老年病对肾功能的影响，按纳入标准对８４份小便进行了４种尿微量蛋白的放射免疫法（ＲＩＡ）测定。结果发现：尿白蛋白（ＵＡｌｂ）、尿β２－微球蛋白（Ｕβ２－Ｍ）、尿免疫球蛋白Ｇ（ＵＩｇＧ）随增龄升高，而尿Ｔａｍｍ－Ｈｏｒｓｆａｌｌ（ＵＴＨＰ）减少。其中ＵＡｌｂ增多与老年人原发性高血压病和Ⅱ型糖尿病有交互作用。说明老年人存在肾老化现象，老年疾病加速肾老化进程。
To investigate the effect of aging and geriatric diseases on renal function, radioimmunoassay (RIA) was performed on 84 urine samples according to the inclusion criteria. The results showed that urinary albumin (UAlb), urinary β2-microglobulin (Uβ2-M) and urinary immunoglobulin G (UIgG) increased with age and urinary Tamm-Horsfall (UTHP) decreased. Which UAlb increased with the elderly with essential hypertension and type Ⅱ diabetes have interaction. Description elderly elderly renal aging phenomenon, accelerated aging of the aging process of kidney disease.