随着新手术技术的引入、放疗技术的改进以及化疗的应用,近十几年来,头颈部鳞癌的局部区域控制率已大大提高。然而患者的最终生存率并无明显改善,主要原因是远处转移和第二原发癌的发生率相对增加。 第二原发癌的诊断标准必须经组织学检查证实, With the introduction of new surgical techniques, the improvement of radiotherapy techniques and the application of chemotherapy, the control of the local area of ​​head and neck squamous cell carcinoma has been greatly increased over the past decade. However, there was no significant improvement in the final survival of patients, mainly due to the relative increase in distant metastasis and second primary cancer. The second primary cancer diagnostic criteria must be confirmed by histological examination,