生物样品中甲基锡化合物检测方法研究进展

来源 :中国职业医学 | 被引量 : 0次 | 上传用户:n131421d
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有机锡是锡和碳元素直接结合形成的金属有机化合物,被广泛应用于化工和农业行业,用作塑料制品的稳定剂、工业催化剂、农业杀虫剂、防腐剂和船体防污涂料等。其中甲基硫醇锡塑料热稳定剂因效果好、用量少、透明度高而被广泛使用。其主要成分是二甲基锡、一甲基锡及其衍生物。二甲基锡和一甲基锡的毒性很低,但在稳定剂合成过程中通常伴生三甲基锡副产物。三甲基锡易挥发,兼有脂溶性和水溶性,可经呼吸道、皮肤和消化道完全吸收,小鼠和兔的经口 Organotins are metal organic compounds formed by the direct combination of tin and carbon. They are widely used in the chemical and agricultural industries as stabilizers for plastic products, industrial catalysts, agricultural pesticides, preservatives, and hull antifouling paints. Among them, methyl mercaptide tin plastic heat stabilizer is widely used because of its good effect, less dosage and high transparency. Its main components are dimethyltin, monomethyltin and its derivatives. Methyltin and monomethyltin are less toxic, but they are usually accompanied by trimethyltin by-products during the stabilizer synthesis. Trimethyltin is volatile, both fat-soluble and water-soluble, can be completely absorbed through the respiratory tract, skin and digestive tract, mice and rabbits oral
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