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肺吸虫病异常感染方式的研究对全面了解肺吸虫的生活史、流行病学及病理学有一定的重要意义。作者采用A、B、C、D、E、五种方式进行研究,对主要结果进行分析及讨论。其中E组感染方式。手头文献尚未见有报道。 A组:犬吞食4—80天不同虫龄及不同成熟程度的虫体,除子宫内已有虫卵的成虫外,均可经口感染。虫体越小,感染性越强。虫体成熟的时间与经口感染囊蚴的时间相似。 B组:同一批虫体反复感染5只犬,其虫龄自5—71天,结果同A组。 C组:犬吞食感染有肺吸虫的大白鼠腹背肌,可以感染肺吸虫病,虫体在犬体内可正常发育。 D组:人工脱囊的后尾蚴经股静脉接种后,虫体在肺内成囊的时间较早一星期左右,但发育成熟的时间与经口感染囊蚴相似。部分幼虫在肺内向胸腔、腹腔移行,引起胸膜炎、浅表性肝炎等病变。 E组:人工脱囊的后尾蚴经右眼眶上壁接种在颅前窝,除了在脑内引起虫窦外,第3天在肺内已出现幼虫。幼虫亦可移行入胸腔、腹腔,但颈部肌肉无虫性病变,提示虫体可能从血道由脑入肺。本文首次提出并总结了幼虫与囊蚴经口感染病理变化的区别。
Paragonimiasis of abnormal infection way to understand the history of paragonimiasis, epidemiology and pathology have some important significance. The author uses A, B, C, D, E five ways to study, the main results of the analysis and discussion. Which group E infection way. There are no reports on hand. Group A: Canine swallows 4-80 days different worm stages and different degrees of maturity of insects, in addition to adult worms within the uterus may be infected by the mouth. The smaller the parasites, the more infective. The timing of maturation of the parasites is similar to the time of oral infection of metacercaria. Group B: In the same batch of worms, 5 dogs were repeatedly infected with 5-6 days of insects and the result was the same as that in group A. Group C: Canine swallows the abdominal muscles of the rats infected with paragonimiasis, which can infect paragonimiasis, and the parasites can develop normally in dogs. In group D, the lacunar lacunar lacunar cells were inoculated into femoral vein more than one week earlier after they were inoculated through the femoral vein, but the maturation time was similar to that of orally infected metacercariae. Some larvae in the lungs to the chest, abdominal migration, causing pleurisy, superficial hepatitis and other lesions. Group E: Artificial exserted cercariae were inoculated into the anterior cranial fossa through the superior orbital wall. In addition to causing the parasite sinus in the brain, larvae appeared in the lungs on the third day. Larvae can also migrate into the thorax, abdominal cavity, but non-nematicidal neck muscle lesions, suggesting that parasites may be from the bloodstream of the brain into the lungs. This paper presents for the first time and summarizes the larvae and metacercaria infection of the pathological changes of the difference.