目的:对米非司酮配伍米索前列醇用于63例孕6~14周稽留流产刮宫术前的宫颈准备疗效进行分析。方法:采用63例孕6~14周稽留流产刮宫术前分次口服米非司酮150mg配伍米索前列醇0.6mg(36小时后顿服)作为甲组,随机选择63例稽留流产刮宫术前应用利多卡因注射两侧宫颈旁作为乙组,两组进行比较。结果:两组比较,甲组对宫颈有明显的软化作用(7.1±0.5)cm,手术时间缩短(10.8±5.2)min,无明显“人工流产综合征”症状出现(0),术中出血明显减少(46.6±10.3)ml,2次刮宫率降低3.94%;乙组对宫颈软化作用差(5.8±0.7)cm,手术时间(18.6±8.3)min,出现“人工流产综合征”症状35例(58.3%),术中出血(82.8±18.2)ml,2次刮宫率16.67%。结论:稽留流产刮宫术前服用米非司酮配伍米索前列醇能安全、有效促进宫颈软化、缩短手术时间、减少人工流产综合征、减少术中出血量、降低2次刮宫率。 OBJECTIVE: To analyze the efficacy of mifepristone and misoprostol for cervical preparation before 63 cases of pregnancy-induced abortion from 6 to 14 weeks. Methods: Sixty-three cases of pregnancy-induced abortion with curettage between 6 and 14 weeks were randomly divided into three groups: 150 cases of mifepristone plus 0.6 mg of misoprostol (Dayun served after 36 hours) Application of lidocaine on both sides of the cervix as a group B, the two groups were compared. Results: Compared with the control group, group A had a significant softening effect (7.1 ± 0.5) cm on the cervix and a shorter operative time (10.8 ± 5.2) min, with no obvious symptoms of “induced abortion syndrome” (0) Bleeding was significantly reduced (46.6 ± 10.3) ml and twice curettage rate was 3.94%. In group B, the incidence of cervical softening was (5.8 ± 0.7) cm and the operation time was (18.6 ± 8.3) min, Symptoms in 35 cases (58.3%), intraoperative bleeding (82.8 ± 18.2) ml, 2 curettage rate was 16.67%. Conclusions: Taking mifepristone and misoprostol before taking curettage of abortion is safe and effective for cervix softening, shortening the operation time, reducing the incidence of induced abortion, reducing the amount of intraoperative bleeding and reducing the curettage rate twice.