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目的:观察分析磷酸氯喹联合曲安奈德与白芍总苷联合曲安奈德以及单纯运用曲安奈德治疗口腔扁平苔藓的疗效。方法:采用对比研究方法,以2011年5月-2013年5月在我院口腔科进行治疗的65例典型口腔扁平苔藓的患者为对象,其中23例患者采用磷酸氯喹联合曲安奈德治疗,记为观察组A组;22例患者采用白芍总苷联合曲安奈德治疗,记为观察组B组;另外20例患者采用单纯曲安奈德进行治疗,记为对照组。分别观察治疗前,治疗后1、3个月VAS评分,REU评分以及疗效评定。结果:两组观察组与对照组比较,治疗后1个月VAS评分,REU评分无统计学意义(P>0.05);治疗后3个月VAS评分,REU评分有统计学意义(P>0.05),而两组观察组全程无统计出差异(P>0.05)。疗效比较发现,三组治疗1个月后差异均无统计学意义(P>0.05)。结论:磷酸氯喹与白芍总苷联合曲安奈德治疗口腔扁平苔藓疗效显著。
OBJECTIVE: To observe and analyze the curative effect of triamcinolone acetonide combined with triamcinolone acetonide and total glucosides of paeony on triamcinolone acetonide and triamcinolone acetonide in the treatment of oral lichen planus. Methods: A comparative study was conducted in 65 patients with typical oral lichen planus treated in our department from May 2011 to May 2013, of whom 23 patients were treated with chloroquine phosphate triamcinolone acetonide and recorded For the observation group A group; 22 patients with total glucosides of paeony root combined with triamcinolone acetonide treatment, recorded as observation group B group; the other 20 patients treated with triamcinolone acetonide alone, recorded as control group. The VAS score, REU score and curative effect before and after treatment were observed respectively. Results: There was no significant difference in VAS score and REU score between the two groups at one month after treatment (P> 0.05). The VAS score and REU score at 3 months after treatment were statistically significant (P0.05) , While there was no statistical difference in the two groups (P> 0.05). The results showed that there was no significant difference in the three groups after one month of treatment (P> 0.05). CONCLUSION: Chloroquine phosphate and total glucosides of paeony mix triamcinolone acetonide in the treatment of oral lichen planus.