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本文叙述了用高压液相色谱法测定高原人、高原移居平原人和平原世居人体中游离腺苷酸。西宁地区移居人群、高原世居人群和平原移居人群腺苷酸测定值与平原地区世居人群腺苷酸测定值相比有显著性差异(P<0.01),而随队老干部,自身队员、平原移居老干部和高原世居人体四组相互比较无显著性差异(P>0.05)。本文从机体血清中所测结果表明短期移居平原地区的机体腺苷酸变化不明显,说明高原人群腺苷酸的生物转化速度相应地比平原缓慢,这种原因可能是腺苷酸在细胞内生成减少和细胞耗能量增加造成不同人体细胞内DNA单链中多核苷损伤修复系统存在差异所致。
This article describes the determination of free adenosine in human beings from the plateau, plateau and plains using high pressure liquid chromatography. There was a significant difference (P <0.01) between the adeninemia values of migrants in the Xining area, the native population in the plateau and the plain migrants, and the measured values of adenylate in the native population in the plain areas (P <0.01) There were no significant differences among the four groups (P> 0.05). In this paper, the measured results from the body serum showed that short-term immigration plain adenosine changes in the body is not obvious, indicating that the high population of adenosine acid biotransformation rate correspondingly slower than the plains, this may be caused by adenylyl acid intracellular Reduce and increase the energy consumption of cells caused by different human body DNA single nucleotide in the nucleoside damage repair system due to differences.