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《湖南中医杂志》1987年第6期刊载了杨永琪同志的《川乌积蓄中毒一例》一文。文章报道了一痹证患者,因每天服用含川乌9克的煎剂,累积川乌总量124克而出现中毒症状。笔者阅后对此持有不同看法,特提出与杨永琪同志商榷。 (一)从现有文献看,川乌的主要毒性成分为乌头硷。此物在体内无积蓄现象,一般在24小时之内可经肾脏全部排泄。故川乌不可能引起积蓄中毒。 (二)笔者在县医院工作时治疗的一个病例,亦可说明川乌不会积蓄中毒。现简要介绍如下,以供同道借鉴:
The 6th issue of Hunan Traditional Chinese Medicine in 1987 contained an article by “Yuanwu’s Accumulation of Poisoning” by Comrade Yang Yongqi. The article reported that patients with one-pupillary-hypertension syndrome suffered from poisoning symptoms because they consumed a total of 9 grams of Chuanwu decoction every day and accumulated a total of 124 grams of Chuanwu. After reading this, the author holds different views on this, and he specifically proposed to discuss with Yang Yongqi. (a) From the existing literature, the main toxic component of Chuanwu is Aconitum carp. There is no accumulation of this substance in the body, and it is generally excreted by the kidney within 24 hours. Therefore, Chuanwu cannot cause accumulation of poisoning. (B) The author treated a case in the county hospital, it can also explain that Chuanwu will not accumulate poisoning. The brief introduction is as follows for reference: