患者,女性,67岁.因多饮、多尿、多食,易饥伴消瘦15年,加重1周于1993年10月17日入院.1978年因上述症状诊断为“糖尿病Ⅱ型”,给予饮食治疗及磺脲类降糖药治疗,症状无改善,改用胰岛素治疗症状缓解.1986年因怕冷、乏力、纳差,查T_3、T_4低于正常,促甲状腺素(TSH)增高,诊断为“原发性甲状腺功能低下”,给甲状腺素片替代治疗后症状消失.同年因心慌气短、活动后加重,查Hb46g/L, Patients, female, aged 67. Adulterated with polyhydric, polyuria, polyphagia, easy hunger with weight loss 15 years, an increase of 1 week was admitted to hospital on October 17, 1993. In 1978 due to the above symptoms were diagnosed as “Diabetes Ⅱ type” Diet therapy and sulfonylurea hypoglycemic agents, no improvement in symptoms, switch to insulin treatment of symptoms. 1986 due to fear of cold, fatigue, anorexia, check T_3, T_4 lower than normal, elevated thyroid hormone (TSH), diagnosis As the “primary hypothyroidism” to thyroid hormone replacement therapy symptoms disappear the same year due to palpitation shortness of breath, aggravating after activity, check Hb46g / L,