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作者采用小鼠气雾攻击模型分析了百日咳全细胞菌苗和５种不同的百日咳无细胞菌苗的效力。这种模型是通过可与小鼠鼻腔相连的一套气雾装置，将可控制的连续量的百日咳杆菌送到小鼠的下呼吸道。 作者用百日咳全细胞菌苗和５种不同的百日咳无细胞菌苗分别腹腔免疫小鼠，每只０．５
The authors used the mouse aerosol challenge model to analyze the efficacy of whole-cell B. pertussis and five different B. pertussis cell-free bacterins. In this model, a controlled continuous dose of Bordetella pertussis is delivered to the lower respiratory tract of mice via an aerosol device that can be attached to the mouse nasal cavity. The authors immunized mice intraperitoneally with B. pertussis whole-cell vaccine and 5 different pertussis acellular vaccine, each 0.5