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目的 :评价口服国产阿托氟啶单药及联合方案治疗无法手术或手术后复发、转移的晚期胃癌、肝癌、食管癌和大肠癌的疗效及其毒副反应。方法 :收治晚期消化道肿瘤患者 4 7例 ,随机分组 :单药组 15例 (单用阿托氟啶 )、联合化疗组 2 3例 (用阿托氟啶联合化疗 )以及对照组 9例 (用FT2 0 7联合化疗 )。结果 :单药组有效率 6 6 7% ,联合化疗组 13 0 4 % ,对照组0 %。无严重毒副反应。单药组及治疗组疗效高于对照组。结论 :口服国产阿托氟啶单用或联合治疗对晚期消化道肿瘤疗效肯定 ,毒副反应较小 ,值得进一步研究及扩大应用
OBJECTIVE: To evaluate the efficacy and side effects of orally administered locally-produced atorvastatin and its combination regimen in the treatment of patients with advanced gastric cancer, liver cancer, esophageal cancer and colorectal cancer who have no surgical or postoperative recurrence and metastasis. Methods: Forty-seven patients with advanced gastrointestinal cancer were randomly divided into three groups: single drug group (atenolol alone), combination chemotherapy group (23 cases) and control group (n = 9) With FT2 0 7 combination chemotherapy). Results: The effective rate of single drug group was 66.7%, that of combined chemotherapy group was 134.4%, and that of control group was 0%. No serious side effects. Monotherapy group and treatment group than the control group. Conclusions: Oral domesticated with orofacil alone or in combination treatment for the treatment of advanced gastrointestinal tumors affirmative, fewer side effects, it is worth further study and expand the application