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Background: Avariety of anterior and posterior segment ocular complications following bone marrow transplantation (BMT)have been well documented in adults and children, but retinal complications after BMT in infants have rarely been reported. Case: A 6-month-old male infant developed occlusive microvascular retinopathy after BMT to treat acute lymphocytic leukemia. Observations: Four months after the transplantation, retinal edema, hemorrhage, soft exudates, and neovascularization were found in the posterior pole fundus of the right eye and in the peripheral fundus of the left eye. After oral prednisolone was administered, the retinal lesions regressed and cicatrices with chorioretinal atrophy and fibrous tissue formed. Conclusions: Neovascularization following occlusive microvascular retinopathy after BMT in infant eyes responds well to oral prednisolone. The visual prognosis depends on the foveal involvement of the retinopathy.
Background: Avariety of anterior and posterior segment ocular marrow following bone marrow transplantation (BMT) have been well documented in adults and children, but retinal complications after BMT in infants have rarely been reported. Case: A 6-month-old male infant developed occlusive microvascular retinopathy after BMT to treat acute lymphocytic leukemia. Observations: Four months after the transplantation, retinal edema, hemorrhage, soft exudates, and neovascularization were found in the posterior pole fundus of the right eye and in the peripheral fundus of the left eye. After oral prednisolone was administered, the retinal lesions regressed and cicatrices with chorioretinal atrophy and fibrous tissue formed. Conclusions: Neovascularization following occlusive microvascular retinopathy after BMT in infant eyes responds well to oral prednisolone. The visual prognosis depends on the foveal involvement of the retinopathy.