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目的:探讨尿毒症患者精子超微结构的形态特征。方法:应用扫描电镜观察10例尿毒症患者以及5名正常生育男性的精子。结果: 尿毒症患者精子异常有以下几种类型:①头部异常:包括精子顶体脱落、顶体缺失、核异常、尖头、小头、无头以及双头畸形精子;②颈部异常:包括精子颈部断裂、分离、颈部膨大;③尾部异常:包括线粒体膨大,线粒体缺失,无尾、双尾、短尾、卷尾等形态结构异常精子。正常生育男性精子头部、颈部、尾部形态结构正常。结论:尿毒症患者精子存在精子头部、颈部、尾部等多种形态结构异常。
Objective: To investigate the morphological characteristics of sperm ultrastructure in uremic patients. Methods: Scanning electron microscopy was used to observe the sperm of 10 patients with uremia and 5 normal fertile men. Results: There are the following types of sperm abnormalities in patients with uremia: ① head abnormalities: including sperm acrosome shedding, acrosome loss, nuclear abnormalities, pointed, small head, headless and double-headed malformation sperm; ② neck abnormalities: Including sperm neck fracture, separation, enlargement of the neck; ③ tail abnormalities: including mitochondrial swelling, mitochondrial loss, no tail, two-tailed, short tail, tail and other morphological abnormalities sperm. Normal birth male sperm head, neck, tail morphology is normal. Conclusion: Sperm in uremia patients have many morphological abnormalities such as sperm head, neck and tail.