肌萎缩性侧索硬化症(MND),是一种运动神经原和神经纤维的变性疾病,目前尚无特殊治疗方法。我们应用变构蛇毒(氧化修饰蛇神经毒MN—8)治疗18MND例取得一定疗效,现报告如下。资料与方法一、临床资料:本组18例中,男13例,女5例。年龄25～62岁,平均43.3岁,病程6个月至10年,平均2年。主要症状和体征:肢体无力15例,构音不清8 Amyotrophic lateral sclerosis (MND), a degenerative disease of motor neurons and nerve fibers, is currently no specific treatment. We use allosteric snake venom (oxidized modified snake nerve MN-8) treatment of 18MND cases to obtain a certain effect, are as follows. Materials and Methods First, the clinical data: The group of 18 patients, 13 males and 5 females. Aged 25 to 62 years, mean 43.3 years old, duration of 6 months to 10 years, an average of 2 years. The main symptoms and signs: limb weakness in 15 cases, unclear articulation 8