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[目的]探讨电视胸腔镜肺叶切除术在原发性非小细胞癌肺中的临床治疗价值。[方法]在2006年2月~2011年2月期间某院共收治周围性原发性非小细胞肺癌患者47例,根据患者的意愿和病变范围等情况选择不同的手术方式,采用电视胸腔镜手术治疗患者共28例(VATS组),采用常规开胸手术治疗患者19例(常规开胸组)。两种患者之间进行术中出血量、手术时间、术后胸腔引流量、淋巴结清扫数目、住院时间、住院费用、术后d1白细胞、血清前白蛋白对比分析。[结果]两组患者均术程顺利,术中及术后未发生1例严重并发症,术中出血量、手术时间、术后引流量、住院时间、住院费用等指标两组不同术式患者之间比较差异有统计学意义(P﹤0.05);淋巴结清扫数目两组之间差异无统计学意义(P﹥0.05);术后d1检测白细胞、血清前白蛋白,VATS组白细胞低于常规开胸组,血清前白蛋白高于常规开胸组,两组之间比较差异无统计学意义(P﹥0.05)。[结论]电视胸腔镜肺叶切除术治疗原发性非小细胞肺癌,手术创伤小、急性期反应低利于患者术后恢复,可作为早期原发性非小细胞癌治疗的一种常规有效术式。
[Objective] To investigate the clinical value of video-assisted thoracoscopic lobectomy in the treatment of primary non-small cell lung cancer. [Methods] From February 2006 to February 2011, 47 cases of peripheral primary non-small cell lung cancer were treated in a hospital from January 2006 to February 2011. According to the patients’ wishes and the range of disease, different surgical methods were selected. Twenty-eight patients (VATS group) underwent surgical treatment and 19 patients underwent conventional thoracotomy (conventional thoracotomy group). The amount of intraoperative blood loss, operation time, postoperative chest drainage, the number of lymph node dissection, hospital stay, hospitalization costs, postoperative d1 leukocytes, prealbumin albumin were compared between the two patients. [Results] The two groups of patients were operated smoothly, one case of serious complications occurred during and after operation, the amount of blood loss, operation time, postoperative drainage, hospital stay, hospitalization cost and other indicators of two groups of patients with different surgical procedures (P <0.05). There was no significant difference in the number of lymph node dissection between the two groups (P> 0.05). The leukocyte count, prealbumin, Thoracic and pre-serum albumin levels were higher than those of conventional thoracotomy group. There was no significant difference between the two groups (P> 0.05). [Conclusion] Video-assisted thoracoscopic lobectomy for the treatment of primary non-small cell lung cancer has the advantages of small operative trauma and low response in acute phase, which can be used as a routine and effective surgical treatment of early primary non-small cell carcinoma .