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目的观察乌司他丁联合奥曲肽治疗急性重症胰腺炎的临床效果。方法选取医院收治的急性重症性胰腺炎患者50例为研究对象,随机分为观察组和对照组,每组25例。对照组采用奥曲肽治疗,观察组采用乌司他丁联合奥曲肽治疗。观察比较2组临床效果。结果治疗14 d后,观察组总有效率为96.0%,高于对照组的76.0%,差异有统计学意义(P<0.05)。结论急性重症胰腺炎患者采用乌司他丁联合奥曲肽治疗,能及时有效地清除炎性因子,避免多脏器功能的衰竭,疗效显著,值得临床推广应用。
Objective To observe the clinical effect of ulinastatin combined with octreotide in the treatment of acute severe pancreatitis. Methods Fifty patients with acute severe pancreatitis admitted to the hospital were selected as study subjects and randomly divided into observation group and control group with 25 cases in each group. The control group was treated with octreotide, and the observation group was treated with ulinastatin and octreotide. Observed and compared the clinical effects of two groups. Results After 14 days of treatment, the total effective rate in the observation group was 96.0%, which was significantly higher than that in the control group (76.0%) (P <0.05). Conclusion Acute severe pancreatitis patients treated with ulinastatin combined with octreotide can be timely and effective removal of inflammatory cytokines, to avoid the failure of multiple organ function, the curative effect is significant, worthy of clinical application.