论文部分内容阅读
目的探讨婴儿急性白血病(IAL)的临床与实验室检查特征。方法对1999年12月-2011年6月收治的15例婴儿急性白血病的临床资料进行总结与分析。结果其中急性淋巴细胞白血病(ALL)6例,急性髓系白血病(AML)8例,分类不明1例,其中以M4(4例)、M5(3例)为主。临床表现多样,髓外浸润明显。1例细胞形态学与免疫分型有差异,1例合并染色体异常。放弃治疗者11例,死亡2例,正规治疗的2例于诱导缓解后获完全缓解。结论 IAL预后差,需完善相关检查并不断总结临床资料以提高IAL治愈率。
Objective To investigate the clinical and laboratory features of infant acute leukemia (IAL). Methods From December 1999 to June 2011, 15 cases of infant acute leukemia clinical data were summarized and analyzed. Results There were 6 cases of acute lymphoblastic leukemia (ALL), 8 cases of acute myeloid leukemia (AML) and 1 case of unknown classification. Among them, M4 (4 cases) and M5 (3 cases) were predominant. Various clinical manifestations, extramedullary infiltration. One case of cell morphology and immunophenotyping differences, 1 case of combined chromosomal abnormalities. Abandon treatment in 11 cases, 2 cases of death, 2 cases of formal treatment after induction of remission was completely relieved. Conclusion The prognosis of IAL is poor, so it is necessary to improve the related examinations and to summarize the clinical data to improve the cure rate of IAL.