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为了探讨脑脊液腺苷脱氨酶（ADA）对中枢神经系统白血病（CNSL）的诊断价值，用比色法对7例急性淋巴细胞性白血病（ALL）伴CNSL和14例无CNSL的ALL患儿进行了脑脊液ADA活性的测定并与15例对照儿的测定值比较。结果，无CNSL的ALL患儿的测定值与对照组比较无明显差别（P＞0．05），而伴CNSL的ALL患儿的测定值明显高于无CNSL的ALL患儿和对照儿的测定值（P＜O．05），并随治疗的好转而明显下降，提示脑脊液ADA活性的测定有助于CNSL的诊断及疗效观察。
In order to investigate the diagnostic value of cerebrospinal fluid adenosine deaminase (ADA) for central nervous system leukemia (CNSL), seven cases of acute lymphocytic leukemia (ALL) with CNSL and 14 cases of children with ALL without ALL were analyzed by colorimetry Cerebrospinal fluid ADA activity was measured and compared with the measured value of 15 control children. As a result, there was no significant difference between the children with ALL without CNSL and the control group (P> 0.05), while the children with ALL with CNSL were significantly higher than those without children with CNSL (P <0.05), and with the improvement of treatment decreased significantly, suggesting that the determination of cerebrospinal fluid ADA contribute to the diagnosis of CNSL and efficacy.