超控促排卵(COH)过程中,卵巢反应性低下的发生率约为10％～15％,是不孕症治疗中最难处理的问题之一。目前,卵巢反应性低下尚无统一定义,其发生机理及处理原则也未明确。 本研究将COH中LH高峰或hCG注射日优势卵泡(直径>1.8cm)数少于3者定义为卵巢反应性低下。对12例不明原因不孕患者(既往至少出现2个周期卵巢反应性低下)行COH+IUI治疗,评价芳香化酶抑制剂Lelrozole和FSH在COH中的效 Over-ovulation induction (COH) process, the incidence of ovarian dysfunction is about 10% to 15%, is one of the most difficult problems in the treatment of infertility. At present, there is no uniform definition of low ovarian response, its mechanism of occurrence and treatment principles are not clear. In this study, the LH peak in COH or the number of dominant follicles (diameter> 1.8cm) fewer than 3 in the day of HCI injection was defined as low ovarian response. COH + IUI treatment was performed in 12 patients with unexplained infertility (previous at least 2 cycles of low ovarian response) to evaluate the effect of aromatase inhibitors Lelrozole and FSH in COH