论文部分内容阅读
我国乙肝病毒携带者约1.2亿人,由此引发的慢性乙肝、肝硬化、肝癌数量大,病势严峻,值得国人高度重视。 很多HBV(乙肝病毒)携带者议论:“花了不少钱,用了很多药,就是没疗效,澳抗阳性真是烦死人!”为什么国内外医学界有此难题?原因是目前还没有一种能彻底清除人体乙肝病毒基因(HBV-DNA)的药物。即便是国际公认有效的a-干扰素(用此药须有严格的病例选择),花上数万元,治疗6个月,也只能使30％～50％的患者体内乙肝病毒及e抗原转阴,且HBsAg(表面抗原)阴转率不超过10％,远期有效率也低。
About 120 million people are carriers of hepatitis B virus in our country. The number of chronic hepatitis B, liver cirrhosis and liver cancer caused by this disease is large and the disease is serious. It is worth the people’s attention. Many HBV carriers talk about it: “Spending a lot of money and using a lot of medicine means that there is no curative effect. What is the problem for Australian anti-HIV positive people?” The reason is that there is not a Complete removal of the human hepatitis B virus gene (HBV-DNA) drugs. Even internationally recognized a-interferon (the drug should have a strict case selection), spend tens of thousands of yuan, 6 months of treatment, only 30% to 50% of patients with hepatitis B virus and e antigen Negative, and HBsAg (surface antigen) negative conversion rate of not more than 10%, long-term efficiency is also low.